Medicinal Chemistry WM-CH-S2-E2-MC
The aim of the course is to familiarize the student with the basic concepts of medicinal chemistry. Modern methods of drug design and development will be discussed, as well as ways to deal with problems arising during these processes (problems with solubility and bioavailability). Methods used for the synthesis of drugs and their analogues (classical organic synthesis, combinatorial chemistry, mechanochemistry) will be thoroughly discussed.
(in Polish) Dyscyplina naukowa, do której odnoszą się efekty uczenia się
(in Polish) E-Learning
Term 2021/22_L: (in Polish) E-Learning (pełny kurs) z podziałem na grupy | Term 2022/23_L: (in Polish) E-Learning (pełny kurs) z podziałem na grupy | Term 2024/25_Z: (in Polish) E-Learning |
(in Polish) Grupa przedmiotów ogólnouczenianych
(in Polish) Opis nakładu pracy studenta w ECTS
Subject level
Learning outcome code/codes
Type of subject
Course coordinators
Learning outcomes
EU1 - characterizes modern methods in drug design and development
EU2 - characterizes core methods in drug synthesis
EU3 - analyzes structure-activity relationship
Assessment criteria
For lecture and exercises:
EU1:
A - verification indicates that the student without noticeable imperfections characterizes modern methods in drug design and development
B+ - verification indicates that the student almost correctly characterizes modern methods in drug design and development and does not fulfil the higher grede requirements
B - verification indicates that the student substentially characterizes modern methods in drug design and development and does not fulfil the higher grede requirements
C+ - verification indicates that the student substentially but inconsitently lcharacterizes modern methods in drug design and development and does not fulfil the higher grede requirements
C - verification indicates that the student in most test cases lcharacterizes modern methods in drug design and development and does not fulfil the higher grede requirements
D - verification indicates that the student does not characterize modern methods in drug design and developments and does fulfil the higher grede requirements
EU2:
A - verification indicates that the student without noticeable imperfections characterizes core methods in drug synthesis
B+ - verification indicates that the student almost correctly characterizes core methods in drug synthesis and does not fulfil the higher grede requirements
B - verification indicates that the student substentially characterizes core methods in drug synthesis and does not fulfil the higher grede requirements
C+ - verification indicates that the student substentially but inconsitently characterizes core methods in drug synthesis and does not fulfil the higher grede requirements
C - verification indicates that the student in most test cases characterizes core methods in drug synthesis and does not fulfil the higher grede requirements
D - verification indicates that the student does not characterize core methods in drug synthesis and does fulfil the higher grede requirements
EU3:
A - verification indicates that the student without noticeable imperfections nalyzes structure-activity relationship
B+ - verification indicates that the student almost correctly nalyzes structure-activity relationship and does not fulfil the higher grede requirements
B - verification indicates that the student substentially nalyzes structure-activity relationshipand does not fulfil the higher grede requirements
C+ - verification indicates that the student substentially but inconsitently nalyzes structure-activity relationshipand does not fulfil the higher grede requirements
C - verification indicates that the student in most test cases nalyzes structure-activity relationship and does not fulfil the higher grede requirements
D - verification indicates that the student does not nalyze structure-activity relationship and does fulfil the higher grede requirements
The final grade x is determined by the value st(w) defined as
st(w)= 5, if 4,5 < w; st(w)= 4.5, if 4.25 < w ≤ 4.5; st(w)= 4, if 3.75 < w ≤ 4.25; st(w)= 3.5, if 3.25 < w ≤ 3.75; st(w)= 3, if 2.75 < w ≤ 3.25; st(w)= 2, if w ≤ 2.75
by the n-grades, i.e., numeric values of grades N(A)=5, N(B+)=4.5, N(B)=4, N(C+)=3.5, N(C)=3, N(D)=2, and by the rule:
● if all the n-grades for the associted classes are at least 3 and y is their average, then x is given by x=IN(st((y+z)/2)), where IN is the inverse function
of N, and z is the weighted average of n-grades given to all verifications with weights 2 assigned to exams, and weights 1 assigned to other forms of
verification
● if one of the grades given to the assaciate classes is either D or F, then x=D.
Bibliography
Basic literature:
G. Thomas, Medicinal Chemistry An Introduction, John Wiley & Sons, 2007
Auxiliary literature:
G. Patrick, An Introduction to Medicinal Chemistry, Oxford University Press
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: