Introduction to Medicinal Chemistry WM-CH-S1-E6-WDCHM
The aim of the course is to introduce the student to the basic concepts of medicinal chemistry. The topics regarding design and development of potential therapeutics will be discussed. The methods used in the synthesis and modification of the drug structure, as well as issues related to drug transport will be covered.
(in Polish) Dyscyplina naukowa, do której odnoszą się efekty uczenia się
(in Polish) E-Learning
(in Polish) Grupa przedmiotów ogólnouczenianych
(in Polish) Opis nakładu pracy studenta w ECTS
Subject level
Learning outcome code/codes
Type of subject
Course coordinators
Learning outcomes
EU1 - explains the basic concepts of medicinal chemistry
EU2 - characterizes modern drug design methods
EU3 - characterizes the methods used for the synthesis and transport of drugs
Assessment criteria
EU1-EU3 - written exam
EU1
A - verification indicates that the student without noticeable imperfections explains the basic concepts of medicinal chemistry
B+ - verification indicates that the student almost correctly explains the basic concepts of medicinal chemistry and does not fulfil the higher grade requirements
B - verification indicates that the student substentially explains the basic concepts of medicinal chemistry and does not fulfil the higher grade requirements
C+ - verification indicates that the student substentially but inconsitently explains the basic concepts of medicinal chemistry and does not fulfil the higher grade requirements
C - verification indicates that the student in most test cases explains the basic concepts of medicinal chemistry and does not fulfil the higher grede requirements
D - verification indicates that the student does not explain the basic concepts related to medicinal chemistry and does not fulfil the higher grade requirements
EU2
A - verification indicates that the student without noticeable imperfections characterizes modern drug design methods
B+ - verification indicates that the student almost correctly characterizes modern drug design methods and does not fulfil the higher grade requirements
B - verification indicates that the student substentially characterizes modern drug design methods and does not fulfil the higher grade requirements
C+ - verification indicates that the student substentially but inconsitently characterizes modern drug design methods and does not fulfil the higher grede requirements
C - verification indicates that the student in most test cases characterizes modern drug design methods and does not fulfil the higher grede requirements
D - verification indicates that the student does not characterize modern drug design methods and does not fulfil the higher grade requirements
EU_3
A - verification indicates that the student without noticeable imperfections characterizes the methods used for the synthesis and transport of drugs
B+ - verification indicates that the student almost correctly characterizes the methods used for the synthesis and transport of drugs and does not fulfil the higher grade requirements
B - verification indicates that the student substentiallycharacterizes the methods used for the synthesis and transport of drugs and does not fulfil the higher grade requirements
C+ - verification indicates that the student substentially but inconsitently characterizes the methods used for the synthesis and transport of drugs and does not fulfil the higher grede requirements
C - verification indicates that the student in most test cases characterizes the methods used for the synthesis and transport of drugs and does not fulfil the higher grede requirements
D - verification indicates that the student does not characterize the methods used for the synthesis and transport of drugs and does not fulfil the higher grade requirements
he final grade x is determined by the value st(w) defined as
st(w)= 5, if 4,5 < w; st(w)= 4.5, if 4.25 < w ≤ 4.5; st(w)= 4, if 3.75 < w ≤ 4.25; st(w)= 3.5, if 3.25 < w ≤ 3.75; st(w)= 3, if 2.75 < w ≤ 3.25; st(w)= 2, if w ≤ 2.75
by the n-grades, i.e., numeric values of grades N(A)=5, N(B+)=4.5, N(B)=4, N(C+)=3.5, N(C)=3, N(D)=2, and by the rule:
● if all the n-grades for the associted classes are at least 3 and y is their average, then x is given by x=IN(st((y+z)/2)), where IN is the inverse function
of N, and z is the weighted average of n-grades given to all verifications with weights 2 assigned to exams, and weights 1 assigned to other forms of
verification
● if one of the grades given to the assaciate classes is either D or F, then x=D.
Bibliography
Basic literature:
R. Silverman, The Organic Chemistry of Drug Design and Drug Action, Academic Press, 2014
Auxiliary literature:
G. Patrick, Instant Notes in Medicinal Chemistry, BIOS Scientific Publishers Ltd.
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: